منابع مشابه
Quantitative Peptidomics of Purkinje Cell Degeneration Mice
Cytosolic carboxypeptidase 1 (CCP1) is a metallopeptidase that removes C-terminal and side-chain glutamates from tubulin. The Purkinje cell degeneration (pcd) mouse lacks CCP1 due to a mutation. Previously, elevated levels of peptides derived from cytosolic and mitochondrial proteins were found in adult pcd mouse brain, raising the possibility that CCP1 functions in the degradation of intracell...
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Chronic obstructive pulmonary disease (COPD) is a complex disorder involving both airways and lung parenchyma, usually associated with progressive and poorly reversible airflow limitation. In order to better characterize the phenotypic heterogeneity and the prognosis of patients with COPD, there is currently an urgent need for discovery and validation of reliable disease biomarkers. Within this...
متن کاملAnti-infection peptidomics of amphibian skin.
Peptidomics and genomics analyses were used to study an anti-infection array of peptides of amphibian skin. 372 cDNA sequences of antimicrobial peptides were characterized from a single individual skin of the frog Odorrana grahami that encode 107 novel antimicrobial peptides. This contribution almost triples the number of currently reported amphibian antimicrobial peptides. The peptides could b...
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Analysis of peptides in biological fluids by mass spectrometry holds promise of providing diagnostic and prognostic information for cancer and other diseases. Before this technology is used clinically, it is important to understand its advantages and limitations. These are summarized, along with proposals, on how to proceed in the future.
متن کاملAnti-infection Peptidomics of Amphibian Skin*□S
Peptidomics and genomics analyses were used to study an anti-infection array of peptides of amphibian skin. 372 cDNA sequences of antimicrobial peptides were characterized from a single individual skin of the frog Odorrana grahami that encode 107 novel antimicrobial peptides. This contribution almost triples the number of currently reported amphibian antimicrobial peptides. The peptides could b...
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ژورنال
عنوان ژورنال: EuPA Open Proteomics
سال: 2014
ISSN: 2212-9685
DOI: 10.1016/j.euprot.2014.04.005